Little Microbiology Blog

Green Fluorescent Protein

GFP is comprised of 238 amino acids which will exhibit bright green fluorescence under long wave UV light. GFP is a highly useful tool in biology, as cells can be marked with the gene for GFP and tracked throughout their life. Such methods are used in developmental biology and biomedicine.

GFP expression as seen under UV light in two of these mice. 

There are also derivatives of GFP which produce different colours of fluorescence. Such proteins have been used to make fluorescent drawings using bacteria and GloFish (below).

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